Gurren Lagann S01 E24 I'll Never Forget This Minute, This Second

"Your drill is the drill that will pierce the Heavens!"

Guided by Simon and Nia's feelings for each other, Team Dai-Gurren break through dimensions in search for the Anti-Spirals' homeworld. But after falling into the enemy's trap, they end up losing some of their most precious members, due to its vicious offensive.