Higurashi: When They Cry S01 E04 The Hidden Demon Chapter - Part 4 - Distortion

"It's not paranoia... if they really are trying to kill you!"

Keiichi's despair reaches its peak. After being captured and sedated, he wakes up restrained by Mion and Rena, and they attempt to inject him with a mysterious drug. Keiichi murders them before taking his own life by clawing his throat.