Watch What Happens Live with Andy Cohen - Season 21

Stepping into the late-late slot vacated by David Letterman, Conan O'Brien stars in a show that far outdoes its competition in sheer strangeness. Along with the celebrity interviews and musical numbers typical of late-night talk shows, this program make frequent use of odd walk-on characters and frequent "visits" from celebrity guests.

Late-night TV legend David Letterman hosts an intimate talk show featuring insightful conversations and fun-filled excursions with notable figures.

Trending news, pop culture, social media, original videos and more come together in host Joel McHale's weekly comedy commentary show.

Building on their original talk show, comedian Norm Macdonald and sidekick Adam Eget sit down and chat with celebrity guests about their life, career and views in a somewhat unconventional and often irreverent way.

Each week, Jefferies tackles the week’s top stories from behind his desk and travels the globe to far-off locations to provide an eye opening look at hypocrisy around the world. Featuring interviews, international field pieces, and man on the ground investigations, Jim tackles the news of the day with no-bulls**t candor, piercing insight and a uniquely Aussie viewpoint.

These half-hour specials showcased some of the best up-and-coming comedians of the moment. The show was a pivotal stepping stone for many of today's stand-up stars.

Jerry takes his comedy pals out for coffee in a selection of his classic automobiles. Larry David sums it up best when he says, 'You've finally made a show about nothing.'

Host Chris Hardwick discusses episodes of the AMC television series The Walking Dead with guests, including celebrity fans, cast members, and crew from the series.

Comic Garry Shandling draws upon his own talk show experiences to create the character of Larry Sanders, a paranoid, insecure host of a late night talk show. Larry, along with his obsequious TV sidekick Hank Kingsley and his fiercely protective producer Artie, allows Garry Shandling and his talented writers to look behind the scenes and to show us a convincing slice of behind the camera life.

RuPaul's Drag Race season 7 queens Katya Zamolodchikova and Trixie Mattel in 'UNHhhh.' It's a show about nothing, and yet it's about everything.