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Dr. Malcolm Sayer, a shy research physician, uses an experimental drug to "awaken" the catatonic victims of a rare disease. Leonard is the first patient to receive the controversial treatment. His awakening, filled with awe and enthusiasm, proves a rebirth for Sayer too, as the exuberant patient reveals life's simple but unutterably sweet pleasures to the introverted doctor.

Firefighters ring for help, and here comes the ladder cart; they hitch a horse to it. A second horse-drawn truck joins the first, and they head down the street to a house fire. Inside a man sleeps, he awakes amidst flames and throws himself back on the bed. In comes a firefighter, hosing down the blaze. He carries out the victim, down a ladder to safety. Other firefighters enter the house to save belongings, and out comes one with a baby. The saved man rejoices, but it's not over yet.

When the mysterious woman in the room next door disappears, a debonair 70-year-old ex-spy living in a luxury hotel on the Côte d'Azur is confronted by the demons and darlings of a lurid past in which moviemaking, memories and madness collide.

An ordinary man sees a bright light descend from the sky, and discovers he now has super-intelligence and telekinesis.

A transit worker pulls commuter Peter off railway tracks after he's mugged, but—while he's in a coma—his family mistakenly thinks she's Peter's fiancée, and she doesn't correct them. Things get more complicated when she falls for his brother, who's not quite sure that she's who she claims to be.

Fifteen-year-old Charlotte Flax is tired of her wacky mom moving their family to a different town any time she feels it is necessary. When they move to a small Massachusetts town and Mrs. Flax begins dating a shopkeeper, Charlotte and her 9-year-old sister, Kate, hope that they can finally settle down. But when Charlotte's attraction to an older man gets in the way, the family must learn to accept each other for who they truly are.

Harvard Law student Oliver Barrett IV and music student Jennifer Cavilleri share a chemistry they cannot deny - and a love they cannot ignore. Despite their opposite backgrounds, the young couple put their hearts on the line for each other. When they marry, Oliver's wealthy father threatens to disown him. Jenny tries to reconcile the Barrett men, but to no avail.

Ben and Laura are a passionate but volatile couple who embark on a round-the-world sailing adventure to give their relationship a new start. During their trip, they decide to explore a vast deserted island which they discover off the coast of Chile. Caught in a violent storm, they shelter in an abandoned whaling station for the night but wake up the next morning to find their boat has disappeared. Stranded in a hostile environment with no means of communication, dwindling supplies and winter approaching they must work together in a life and death battle for survival, that will challenge their feelings and change their relationship forever.

In 1918, a young, disillusioned Adolf Hitler strikes up a friendship with a Jewish art dealer while weighing a life of passion for art vs. talent at politics

Born under unusual circumstances, Benjamin Button springs into being as an elderly man in a New Orleans nursing home and ages in reverse. Twelve years after his birth, he meets Daisy, a child who flits in and out of his life as she grows up to be a dancer. Though he has all sorts of unusual adventures over the course of his life, it is his relationship with Daisy, and the hope that they will come together at the right time, that drives Benjamin forward.