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Jack McKee is a doctor with it all: he's successful, he's rich, and he has no problems.... until he is diagnosed with throat cancer. Now that he has seen medicine, hospitals, and doctors from a patient's perspective, he realises that there is more to being a doctor than surgery and prescriptions.

In a suburban landscape, the lives of several families interlace with loss, despair and personal crisis. Esther Gold has lost focus on all but caring for her comatose son, Paul, and neglects her daughter and husband. Lawyer Jim Train is devoted to his career, not his family. Helen Christianson wants to find a new spark in life, while Annette Jennings tries to rebuild hers.

A doctor dealing with the aftermath of his son's death tries to help a troubled young man.

It took a lot of cajoling to get Bob, a recently widowed architect, to go on a blind date at a quirky Irish-Italian eatery. Once there, he's smitten instantly not with his date but with the sharp-witted waitress. Everything seems to be going great until an unbelievable truth is revealed, one that could easily break both of their hearts for good.

Inspired by her mom's rebellious past and a confident new friend, a shy 16-year-old publishes an anonymous zine calling out sexism at her school.

A man reflects on the lost love of his youth and his long-ago journey from Taiwan to America as he begins to reconnect with his estranged daughter.

With her life crashing down around her, Linda attempts to navigate her child's mysterious illness, her absent husband, a missing person, and an increasingly hostile relationship with her therapist.

After her stay-at-home husband leaves her, a workaholic lawyer finds that she is not completely up to the tasks of caring for her young son, ailing father and household all by herself.

Isabelle, a geneticist recovering from a toxic marriage, is raising her only daughter, Zoe, with her contentious ex-husband. Zoe means everything to her mother and so when tragedy strikes the fractured family, Isabelle travels to Russia in seeking the help of a world-renowned fertility physician who Isabelle believes can help bring back her little girl.

A moment of impulsiveness turns Gao Zhilei into a "stay-at-home" individual, but he never expected his life to take a turn in the opposite direction. A series of changes compel him to take on his responsibilities as the head of the family. When life's burdens hit hard, he must confront himself and start anew.