Es werde Licht!

Working-class father John Crowley is finally on the fast track to corporate success when his two young children are diagnosed with Pompe disease—a condition that prevents the body from breaking down sugar. With the support of his wife, John ditches his career and teams with unconventional specialist, Dr. Robert Stonehill to found a bio-tech company and develop a cure in time to save the lives of his children. As Dr. Stonehill works tirelessly to prove the theories that made him the black sheep of the medical community, a powerful bond is forged between the two unlikely allies.

Fred arrives at the doorstep of his beautiful young mistress Velvet after four years apart, claiming to have finally left his wife. But when she rejects his attempts to rekindle their romance, his persistence evolves into obsession — and a dark history between the former lovers comes into focus.

A man reflects on the lost love of his youth and his long-ago journey from Taiwan to America as he begins to reconnect with his estranged daughter.

An aging, out-of-work actress accepts one last job, though the consequences of her decision affect her in ways she didn't consider.

Tom and Mae Garvey are a Tennessee farming couple battling violent floods to save their land. In addition to natural disasters, the Garveys fight to stop a selfish land developer and a local corporation from foreclosing on their farm. While Mae stays at home to care for their children and tend to the crops, Tom finds work as a scab at a steel mill to preserve his family's property.

A woman sexually assaulted by her new boss's brother-in-law tries to move on as if nothing happened, but the night weighs heavily on her mind and body.

Vincent, a young man who suffers from Tourette's syndrome, has just lost his mother. His father, a successful politician, does not want to take care of him and therefore places him into a mental institution. He is put into a room with Alexander, a guy with a compulsive disorder, and is shown around by Marie, an anorectic girl.

Calvin Campbell is a former professional baseball player sent to an early retirement due to his panic attacks at the plate. Even though he had all the talent for the big leagues, he struggles with the curveballs life has thrown him. Today, he mindlessly sleepwalks through his days and the challenge of raising his teenager daughter. His life is in a slow downward spiral when it is suddenly awakened and invigorated by the most unlikely person – Produce, a young-man with Down syndrome who works at the local grocery store.

Agnes and her two sisters struggle through a day in a home overrun by gamblers, thieves, and johns.

In a suburban landscape, the lives of several families interlace with loss, despair and personal crisis. Esther Gold has lost focus on all but caring for her comatose son, Paul, and neglects her daughter and husband. Lawyer Jim Train is devoted to his career, not his family. Helen Christianson wants to find a new spark in life, while Annette Jennings tries to rebuild hers.