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David, a naive graduate student, has volunteered to work as a 'buddy' for people dying of AIDS. Assigned to the intensely political Robert, a lifelong activist whose friends and family have abandoned him following his diagnosis, the two men, each with notably different world views, soon discover common bonds, as David's inner activist awakens and Robert's need for emotional release is fulfilled.

Erik, a loner, finds a friend in Dexter, an eleven-year-old boy with AIDS. They vow to find a cure for AIDS together and save Dexter's life in an eventful summer.

After breaking up with her girlfriend, a nightclub singer, Jane, answers a personal ad from Robin, a real estate agent with AIDS, seeking a cross-country travel partner. On their journey from New York City to Los Angeles, the two stop by Pittsburgh to pick up Jane's friend Holly, who is trying to escape an abusive relationship. With three distinct personalities, the women must overcome their differences to help one another.

While caring for her brother along with her audacious mother, a teenager strikes up an unlikely friendship with an eccentric activist who is protesting one of the most landmark medical cases of all time.

After learning that his terminally ill wife has six months to live, a man welcomes the support of his best friend who moves into their home to help out.

During the summer of 1981, a group of friends in New York are completely unprepared for the onslaught of AIDS. What starts as a rumor about a mysterious "gay cancer" soon turns into a major crisis as, one by one, some of the friends begin to fall ill, leaving the others to panic about who will be next. As death takes its toll, the lives of these friends are forever redefined by an unconditional display of love, hope and courage.

Gia Carangi meteorically rises to modeling fame in the late 1970s but becomes overconsumed by persistent loneliness and drug addiction.

Michael and Robert, two gay men living in Brooklyn, spend their last day together before Robert leaves for Africa on work assignment. Michael still has feelings for his friend Nick, who has AIDS.

Caleb, a South Florida teen, loves his camera, his weed and his grandmother. On the eve of his high school graduation, everything changes when he's exposed to HIV. While he waits three months for his results, Caleb finds love in the most unlikely of places.

Jeffrey, a gay man living in New York City with an overwhelming fear of contracting AIDS, concludes that being celibate is the only option to protect himself. As fate would have it, shortly after his declaration of a sex-free existence, he meets the handsome Steve Howard, his dream man -- except for his HIV-positive status. Facing this dilemma, Jeffrey turns to his best friend and an outrageous priest for guidance.