Cells at Work!! The Return of the Strongest Enemy: A Huge Uproar in the Body’s Bowels!

Yuuta and Rikka are in their third year of high school. One day in Spring, Touka declares that she will take Rikka to Italy with her, as her job has stabilized there and thinks they should migrate together as a family. Touka is also worried about Rikka not being competent enough to advance to universities in Japan. The gangs from the club suggested Yuuta, who doesn't want to be separated, to elope with Rikka!! A runaway drama throughout Japan begins.

With the Tendos, the Saotomes, Ryoga, Shampoo and Ukyo misinterpreting Tatewake Kuno's invitation to his two loves, Akane and 'The Pig Tailed Girl', to try his new yacht, a whole new episode of chaos begins in the already unstable lives of the Saotome/Tendo clan. A mysterious shadow kidnaps first Akane's sister Kasumi, then continues on until all the girls disappear. All except everyone's favorite hydrotranssexual.

The special takes place during the two year before the Straw Hats reunite on Sabody. Luffy is currently in Rusukaina training to get stronger to take on the New World. However the training is interrupted when Hancock's sisters, Marigold and Sandersonia, are kidnapped by the Byrnndi World, a pirate who was locked away on Level 6 of Impel Down but escaped during Luffy's invasion to save Ace, in order to lure Hancock to him and use her as a hostage against the World Government due to her Shichibukai status. Thus Luffy and Hancock head off to confront him and save Hancock's sisters.

The Straw Hats embark on a dangerous trip to the sky where their destination comes straight out of a fairytale. The island of Skypiea and its grand city of gold await among the clouds, but a clash of winged clans and a man who calls himself God won’t make things easy! Only Luffy can resist this God’s mighty power and light the mysteries of the past.

A giant whale appears and flies above Sakura New Town. With the whale’s sound of crying, some changes occur to Kenta Amano and Yokai.

Shin-chan is approached by his time-traveling future bride-to-be Tamiko, who asks him to help save his adult self from the ruler of Neo Tokio.

The Noharas win a vacation to the Kingdom of Buri Buri -- but the whole thing was just a clever ploy by an evil organization to kidnap Shin-chan!

The Noharas go on an Action Mask-themed cruise, where all the grown-ups get kidnapped by a gang of monkeys. It's up to the kids to rescue them!

Experience the inspiring moments that launched Luffy and the first four members of his crew on their grand adventure to find the One Piece! It’s all here—from Shanks giving Luffy the straw hat, to Nami facing the Fish-Men at her hometown. Along the way, Zoro finds his swordsman’s zeal, Usopp pays for his pranks, and Sanji sizzles up the Baratie. Join the crew where it all began in the waters of East Blue.

Ryo Saeba works the streets of Tokyo as the City Hunter. He's a "sweeper" and with his sidekick Kaori Makimura, he keeps the city clean. People hire the City Hunter to solve their dangerous problems, which he does with a Colt Python. When Ryo's not working on a case, he's working on getting the ladies, and Kaori must keep him in check with her trusty 10 kg hammer.